Genotype and Tumor Locus Determine Expression Profile of Pseudohypoxic Pheochromocytomas and Paragangliomas

Pheochromocytomas (PHEOs) and paragangliomas (PGLs) related to mutations in the mitochondrial succinate dehydrogenase (SDH) subunits A, B, C, and D, SDH complex assembly factor 2, and the von Hippel-Lindau (VHL) genes share a pseudohypoxic expression profile. However, genotype-specific differences i...

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Main Authors: Uma Shankavaram, Stephanie M.J. Fliedner, Abdel G. Elkahloun, Jenifer J. Barb, Peter J. Munson, Thanh T. Huynh, Joey C. Matro, Hana Turkova, W. Marston Linehan, Henri J. Timmers, Arthur S. Tischler, James F. Powers, Ronald de Krijger, Bora E. Baysal, Martina Takacova, Silvia Pastorekova, David Gius, Hendrik Lehnert, Kevin Camphausen, Karel Pacak
פורמט: Article
שפה:English
יצא לאור: Elsevier 2013-04-01
סדרה:Neoplasia: An International Journal for Oncology Research
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S1476558613800504