Approaches to Configuration Determinations of Flexible Marine Natural Products: Advances and Prospects

Approaches to Configuration Determinations of Flexible Marine Natural Products: Advances and Prospects

Flexible marine natural products (MNPs), such as eribulin and bryostatin, play an important role in the development of modern marine drugs. However, due to the multiple chiral centers and geometrical uncertainty of flexible systems, configuration determinations of flexible MNPs face great challenges...

Full description

Bibliographic Details
Main Authors: Zong-Qing Huo, Feng Zhu, Xing-Wang Zhang, Xiao Zhang, Hong-Bao Liang, Jing-Chun Yao, Zhong Liu, Gui-Min Zhang, Qing-Qiang Yao, Guo-Fei Qin
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Marine Drugs
Subjects:
flexible marine natural products
configuration determinations
X-ray single-crystal diffraction
NMR-based methods
circular dichroism-based methods
quantum computational chemistry-based methods
Online Access:https://www.mdpi.com/1660-3397/20/5/333

Internet

https://www.mdpi.com/1660-3397/20/5/333

Similar Items