MitoTEMPOL Inhibits ROS-Induced Retinal Vascularization Pattern by Modulating Autophagy and Apoptosis in Rat-Injected Streptozotocin Model

MitoTEMPOL Inhibits ROS-Induced Retinal Vascularization Pattern by Modulating Autophagy and Apoptosis in Rat-Injected Streptozotocin Model

Diabetic retinopathy leads to retinal malfunction, blindness, and reduced quality of life in adult diabetes patients. The involvement of reactive oxygen species (ROS) regulation stimulated by high blood glucose levels opens the opportunity for ROS modulator agents such as MitoTEMPOL. This study aims...

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Bibliographic Details
Main Authors: Rova Virgana, Nur Atik, Julia Windi Gunadi, Evelyn Jonathan, Dona Erisa Ramadhani, Ray Sebastian Soetadji, Hanna Goenawan, Ronny Lesmana, Arief Kartasasmita
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Life
Subjects:
diabetic retinopathy
MitoTEMPOL
mitochondria-targeted antioxidant
retinal vascularization
autophagy
apoptosis
Online Access:https://www.mdpi.com/2075-1729/12/7/1061

Internet

https://www.mdpi.com/2075-1729/12/7/1061

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