Active Nuclear Import of Membrane Proteins Revisited

It is poorly understood how membrane proteins destined for the inner nuclear membrane pass the crowded environment of the Nuclear Pore Complex (NPC). For the Saccharomyces cerevisiae proteins Src1/Heh1 and Heh2, a transport mechanism was proposed where the transmembrane domains diffuse through the m...

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Bibliographic Details
Main Authors: Justyna K. Laba, Anton Steen, Petra Popken, Alina Chernova, Bert Poolman, Liesbeth M. Veenhoff
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/4/4/653