Platelet-derived growth factor-BB and white matter hyperintensity burden in APOE4 carriers
Background: The apolipoprotein-e4 (APOE4) gene increases risk for developing late-onset Alzheimer's disease (AD) and has been linked to increased microvascular dysfunction, including pericyte degeneration and blood-brain barrier breakdown. Platelet-derived growth factor-BB (PDGF-BB) is a glycop...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Cerebral Circulation - Cognition and Behavior |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666245022000964 |