LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans

LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans

The ubiquitin-like proteins Atg8/LC3/GABARAP are required for multiple steps of autophagy, such as initiation, cargo recognition and engulfment, vesicle closure and degradation. Most of LC3/GABARAP functions are considered dependent on their post-translational modifications and their association wit...

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Bibliographic Details
Main Authors: Romane Leboutet, Céline Largeau, Leonie Müller, Magali Prigent, Grégoire Quinet, Manuel S Rodriguez, Marie-Hélène Cuif, Thorsten Hoppe, Emmanuel Culetto, Christophe Lefebvre, Renaud Legouis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
Atg8/LC3/GABARAP
autophagy
C. elegans
development
CRISPR-Cas9
S. cerevisiae
Online Access:https://elifesciences.org/articles/85748

Internet

https://elifesciences.org/articles/85748

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