Mass Cytometry Identifies Expansion of T-bet+ B Cells and CD206+ Monocytes in Early Multiple Sclerosis

Mass Cytometry Identifies Expansion of T-bet+ B Cells and CD206+ Monocytes in Early Multiple Sclerosis

Multiple sclerosis (MS) is an immune-driven demyelinating disease of the central nervous system. Immune cell features are particularly promising as predictive biomarkers due to their central role in the pathogenesis but also as drug targets, even if nowadays, they have no impact in clinical practice...

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Bibliographic Details
Main Authors: Laura Couloume, Juliette Ferrant, Simon Le Gallou, Marion Mandon, Rachel Jean, Nadège Bescher, Helene Zephir, Gilles Edan, Eric Thouvenot, Aurelie Ruet, Marc Debouverie, Karin Tarte, Patricia Amé, Mikael Roussel, Laure Michel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
biomarker
multiple sclerosis
mass cytometry
immunology
B cells
monocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.653577/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.653577/full

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