Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland

Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland

Abstract Thyroid hormone (3,5,3’-triiodothyronine, T3) is a key regulator of pituitary gland function. The response to T3 is thought to hinge crucially on interactions of nuclear T3 receptors with enhancers but these sites in pituitary chromatin remain surprisingly obscure. Here, we investigate geno...

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Bibliographic Details
Main Authors: Young-Wook Cho, Yulong Fu, Chen-Che Jeff Huang, Xuefeng Wu, Lily Ng, Kevin A. Kelley, Kristen R. Vella, Anders H. Berg, Anthony N. Hollenberg, Hong Liu, Douglas Forrest
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05546-y

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https://doi.org/10.1038/s42003-023-05546-y

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