Mechanism underlying hippocampal long-term potentiation and depression based on competition between endocytosis and exocytosis of AMPA receptors
Abstract N-methyl-D-aspartate (NMDA) receptor-dependent long-term potentiation (LTP) and long-term depression (LTD) of signal transmission form neural circuits and thus are thought to underlie learning and memory. These mechanisms are mediated by AMPA receptor (AMPAR) trafficking in postsynaptic neu...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-09-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-71528-3 |