Mechanistic Investigation of WWOX Function in NF-kB-Induced Skin Inflammation in Psoriasis

Mechanistic Investigation of WWOX Function in NF-kB-Induced Skin Inflammation in Psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation, aberrant differentiation of keratinocytes, and dysregulated immune responses. WW domain-containing oxidoreductase (WWOX) is a non-classical tumor suppressor gene that regulates multiple cellular processes...

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Bibliographic Details
Main Authors: Min-Jeong Shin, Hyun-Sun Kim, Pyeongan Lee, Na-Gyeong Yang, Jae-Yun Kim, Yun-Su Eun, Whiin Lee, Doyeon Kim, Young Lee, Kyung-Eun Jung, Dongkyun Hong, Jung-Min Shin, Sul-Hee Lee, Sung-Yul Lee, Chang-Deok Kim, Jung-Eun Kim
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
psoriasis
WWOX
poly(I:C)
NF-kB
PKC
calcium ion
Online Access:https://www.mdpi.com/1422-0067/25/1/167

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https://www.mdpi.com/1422-0067/25/1/167

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