Diagnostics of Mutations in MMR/<i>EPCAM</i> Genes and Their Role in the Treatment and Care of Patients with Lynch Syndrome

Diagnostics of Mutations in MMR/<i>EPCAM</i> Genes and Their Role in the Treatment and Care of Patients with Lynch Syndrome

Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is a disorder caused by an autosomal dominant heterozygous germline mutation in one of the DNA mismatch repair (MMR) genes. Individuals with LS are at an increased risk of developing colorectal and extracolonic can...

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Bibliographic Details
Main Authors: Joanna Sobocińska, Tomasz Kolenda, Anna Teresiak, Natalia Badziąg-Leśniak, Magda Kopczyńska, Kacper Guglas, Anna Przybyła, Violetta Filas, Elżbieta Bogajewska-Ryłko, Katarzyna Lamperska, Andrzej Mackiewicz
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Diagnostics
Subjects:
Lynch syndrome
hereditary cancer
colorectal cancer
MMR
diagnostics
IHC
Online Access:https://www.mdpi.com/2075-4418/10/10/786

Internet

https://www.mdpi.com/2075-4418/10/10/786

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