Segmentation of cellular ultrastructures on sparsely labeled 3D electron microscopy images using deep learning

Segmentation of cellular ultrastructures on sparsely labeled 3D electron microscopy images using deep learning

Focused ion beam-scanning electron microscopy (FIB-SEM) images can provide a detailed view of the cellular ultrastructure of tumor cells. A deeper understanding of their organization and interactions can shed light on cancer mechanisms and progression. However, the bottleneck in the analysis is the...

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Bibliographic Details
Main Authors: Archana Machireddy, Guillaume Thibault, Kevin G. Loftis, Kevin Stoltz, Cecilia E. Bueno, Hannah R. Smith, Jessica L. Riesterer, Joe W. Gray, Xubo Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Bioinformatics
Subjects:
electron microscopy
segmentation
deep neural network
cell boundary
subcellular ultrastructure
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2023.1308708/full

Internet

https://www.frontiersin.org/articles/10.3389/fbinf.2023.1308708/full

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