Conditional Dnmt3b deletion in hippocampal dCA1 impairs recognition memory

Conditional Dnmt3b deletion in hippocampal dCA1 impairs recognition memory

Abstract Aim Active changes in neuronal DNA methylation and demethylation appear to act as controllers of synaptic scaling and glutamate receptor trafficking in learning and memory formation. DNA methyltransferases (DNMTs), including proteins encoded by Dnmt1, Dnmt3a and Dnmt3b, are dominant enzymes...

Full description

Bibliographic Details
Main Authors: Qingnuan Kong, Ming Yu, Meng Zhang, Chuang Wei, Huating Gu, Shaoyang Yu, Wei Sun, Nan Li, Yu Zhou
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Molecular Brain
Subjects:
Dnmt3b
Memory
Hippocampus
Object-place recognition
Online Access:http://link.springer.com/article/10.1186/s13041-020-00574-9

Internet

http://link.springer.com/article/10.1186/s13041-020-00574-9

Similar Items