Intronic gRNAs for the Construction of Minimal Gene Drive Systems

Gene drives are promising tools for the genetic control of insect vector or pest populations. CRISPR-based gene drives are generally highly complex synthetic constructs consisting of multiple transgenes and their respective regulatory elements. This complicates the generation of new gene drives and...

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Bibliographic Details
Main Authors: Alexander Nash, Paolo Capriotti, Astrid Hoermann, Phillipos Aris Papathanos, Nikolai Windbichler
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.857460/full