Crosstalk between autophagy inhibitors and endosome-related secretory pathways: a challenge for autophagy-based treatment of solid cancers

Abstract Autophagy is best known for its role in organelle and protein turnover, cell quality control, and metabolism. The autophagic machinery has, however, also adapted to enable protein trafficking and unconventional secretory pathways so that organelles (such as autophagosomes and multivesicular...

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Bibliographic Details
Main Authors: Martina Raudenska, Jan Balvan, Michal Masarik
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-021-01423-6