Dibutyl phthalate promotes juvenile Sertoli cell proliferation by decreasing the levels of the E3 ubiquitin ligase Pellino 2

Dibutyl phthalate promotes juvenile Sertoli cell proliferation by decreasing the levels of the E3 ubiquitin ligase Pellino 2

Abstract Background A previous study showed that dibutyl phthalate (DBP) exposure disrupted the growth of testicular Sertoli cells (SCs). In the present study, we aimed to investigate the potential mechanism by which DBP promotes juvenile SC proliferation in vivo and in vitro. Methods Timed pregnant...

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Bibliographic Details
Main Authors: Tan Ma, Jiwei Hou, Yuan Zhou, Yusheng Chen, Jiayin Qiu, Jiang Wu, Jie Ding, Xiaodong Han, Dongmei Li
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Environmental Health
Subjects:
Dibutyl phthalate
Monobutyl phthalate
Sertoli cells
Apoptosis
Peli2
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12940-020-00639-1

Internet

http://link.springer.com/article/10.1186/s12940-020-00639-1

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