Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer’s disease: Experimental approach and therapeutic implications

Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer’s disease: Experimental approach and therapeutic implications

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease of aging and currently has no cure. Its onset and progression are influenced by multiple factors. There is growing consensus that successful treatment will rely on simultaneously targeting multiple pathological features of AD....

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Bibliographic Details
Main Authors: Jun eWang, Weina eBi, Alice eCheng, Daniel eFreire, Prashant eVempati, Wei eZhao, Bing eGong, Elsa eJanle, Tzu-Ying eChen, Mario eFerruzzi, James eSchmeidler, Lap eHo, Giulio Maria Pasinetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Grape Seed Extract
Polyphenols
resveratrol
Alzheimer's disease (AD)
Grape Juice
J20 mice
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00042/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00042/full

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