YME1L-mediated mitophagy protects renal tubular cells against cellular senescence under diabetic conditions
Abstract Background The senescence of renal tubular epithelial cells (RTECs) is crucial in the progression of diabetic kidney disease (DKD). Accumulating evidence suggests a close association between insufficient mitophagy and RTEC senescence. Yeast mitochondrial escape 1-like 1 (YME1L), an inner mi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | Biological Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40659-024-00487-0 |