Carrier molecules and extraction of circulating tumor DNA for next generation sequencing in colorectal cancer

The aims of the study were: i) to compare circulating tumor DNA (ctDNA) yields obtained by different manual extraction procedures, ii) to evaluate the addition of various carrier molecules into the plasma to improve ctDNA extraction recovery, and iii) to use next generation sequencing (NGS) technolo...

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Bibliographic Details
Main Authors: Martin Beránek, Igor Sirák, Milan Vošmik, Jiří Petera, Monika Drastíková, Vladimír Palička
Format: Article
Language:English
Published: Karolinum Press 2016-08-01
Series:Acta Medica
Subjects:
Online Access:http://actamedica.lfhk.cuni.cz/59/2/0054/