GraS signaling in Staphylococcus aureus is regulated by a single D35 residue in the extracellular loop

ABSTRACT Bacterial two-component systems are crucial features of bacterial pathogens such as methicillin-resistant Staphylococcus aureus to overcome environmental and antimicrobial stresses by activating regulons to interfere with the bactericidal mechanisms. GraRS is a unique subset of two-componen...

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Bibliographic Details
Main Authors: Junho Cho, Adhar C. Manna, Helah S. Snelling, Ambrose L. Cheung
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01982-23