USP9X Is Required to Maintain Cell Survival in Response to High-LET Radiation

USP9X Is Required to Maintain Cell Survival in Response to High-LET Radiation

Ionizing radiation (IR) principally acts through induction of DNA damage that promotes cell death, although the biological effects of IR are more broad ranging. In fact, the impact of IR of higher-linear energy transfer (LET) on cell biology is generally not well understood. Critically, therefore, t...

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Bibliographic Details
Main Authors: Catherine M. Nickson, Maria Rita Fabbrizi, Rachel J. Carter, Jonathan R. Hughes, Andrzej Kacperek, Mark A. Hill, Jason L. Parsons
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
centrosome
DNA damage
DNA repair
ionizing radiation
protons
ubiquitin
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.671431/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.671431/full

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