Insights into an NEk2 inhibitory profile of nitidine chloride by molecular docking and biological evaluation
Abstract Deregulation of NEK2(NIMA-related serine/threonine 2) confers chemotherapeutic resistance to apoptosis and is closely correlated with poor prognosis in hepatocellular carcinoma (HCC). Here, we find that nanoparticles are prepared through hemisynthesis from natural nitidine chloride (NC) wit...
Main Authors: | Danni Li, Jiahao Lu, Qiying Zhang, Yuzhu Zhou, Long Li, Hua Zhu, Tong Li |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-10-01
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Series: | BMC Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13065-022-00870-6 |
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