Gal-3BP Negatively Regulates NF-κB Signaling by Inhibiting the Activation of TAK1

Galectin-3-binding protein (Gal-3BP) is a member of the family of scavenger receptor cysteine-rich (SRCR) domain-containing proteins, which are associated with the immune system. However, the functional roles and signaling mechanisms of Gal-3BP in host defense and the immune response remain largely...

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Bibliographic Details
Main Authors: Chang-Soo Hong, Mi-Ra Park, Eun-Gene Sun, Wonyoung Choi, Jun-Eul Hwang, Woo-Kyun Bae, Joon Haeng Rhee, Sang-Hee Cho, Ik-Joo Chung
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01760/full