False discovery rate estimation using candidate peptides for each spectrum

False discovery rate estimation using candidate peptides for each spectrum

Abstract Background False discovery rate (FDR) estimation is very important in proteomics. The target-decoy strategy (TDS), which is often used for FDR estimation, estimates the FDR under the assumption that when spectra are identified incorrectly, the probabilities of the spectra matching the targe...

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Bibliographic Details
Main Authors: Sangjeong Lee, Heejin Park, Hyunwoo Kim
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Bioinformatics
Subjects:
Target-decoy strategy
False discovery rate
Proteomics
Tandem mass spectrometry
Online Access:https://doi.org/10.1186/s12859-022-05002-4

Internet

https://doi.org/10.1186/s12859-022-05002-4

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