Design, Synthesis, and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines

Design, Synthesis, and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines

Based on the marine natural products piperafizine B, XR334, and our previously reported compound <b>4m</b>, fourteen novel 3,6-diunsaturated 2,5-diketopiperazine (2,5-DKP) derivatives (<b>1</b>, <b>2</b>, <b>4</b>–<b>6</b>, <b>8</b...

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Bibliographic Details
Main Authors: Xiaolin Li, Tianrong Xun, Huayan Xu, Xiaoyan Pang, Bin Yang, Junfeng Wang, Xuefeng Zhou, Xiuping Lin, Suiyi Tan, Yonghong Liu, Shengrong Liao
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Marine Drugs
Subjects:
2,5-diketopiperazine derivative
intermolecular hydrogen bond
liposolubility
electron property
anticancer activity
Online Access:https://www.mdpi.com/1660-3397/21/6/325

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https://www.mdpi.com/1660-3397/21/6/325

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