Simulation atomic force microscopy for atomic reconstruction of biomolecular structures from resolution-limited experimental images.

Atomic force microscopy (AFM) can visualize the dynamics of single biomolecules under near-physiological conditions. However, the scanning tip probes only the molecular surface with limited resolution, missing details required to fully deduce functional mechanisms from imaging alone. To overcome suc...

Full description

Bibliographic Details
Main Authors: Romain Amyot, Arin Marchesi, Clemens M Franz, Ignacio Casuso, Holger Flechsig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009970