Paternal dietary ratio of n-6: n-3 polyunsaturated fatty acids programs offspring leptin expression and gene imprinting in mice

Paternal dietary ratio of n-6: n-3 polyunsaturated fatty acids programs offspring leptin expression and gene imprinting in mice

BackgroundThis study determined the effects of the paternal dietary ratio of n-6: n-3 polyunsaturated fatty acids (PUFAs) on leptin expression in the offspring and associated gene imprinting in a mouse model.MethodsThree- to four-week-old male C57BL/6J mice (F0) were fed an n-3 PUFA-deficient (n-3 D...

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Bibliographic Details
Main Authors: Qiaoyu Shi, Xuanyi Liu, Xiuqin Fan, Rui Wang, Kemin Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Nutrition
Subjects:
gene imprinting
paternal programming
n-3 fatty acids
leptin
offspring
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.1043876/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.1043876/full

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