Urinary markers of Mycobacterium tuberculosis and dysbiosis in paediatric tuberculous meningitis cases undergoing treatment

Urinary markers of Mycobacterium tuberculosis and dysbiosis in paediatric tuberculous meningitis cases undergoing treatment

Abstract Background The pathogenesis of tuberculous meningitis (TBM) involves infection by Mycobacterium tuberculosis in the meninges and brain. However, recent studies have shown that the immune response and inflammatory processes triggered by TBM can have significant effects on gut microbiota. Dis...

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Bibliographic Details
Main Authors: Simon Isaiah, Du Toit Loots, A. Marceline Tutu van Furth, Elmarie Davoren, Sabine van Elsland, Regan Solomons, Martijn van der Kuip, Shayne Mason
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Gut Pathogens
Subjects:
Urine
Microbiota
Paediatric
Tuberculous meningitis (TBM)
Metabolomics
Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Online Access:https://doi.org/10.1186/s13099-024-00609-9

Internet

https://doi.org/10.1186/s13099-024-00609-9

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