The Influence of Intracellular Glutathione Levels on the Induction of Nrf2-Mediated Gene Expression by α-Dicarbonyl Precursors of Advanced Glycation End Products

α-Dicarbonyl compounds, particularly methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG), are highly reactive precursors for the formation of advanced glycation end products (AGEs). They are formed in vivo and during food processing. This study aimed to investigate the role of intracellul...

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Bibliographic Details
Main Authors: Liang Zheng, Katja C. W. van Dongen, Wouter Bakker, Ignacio Miro Estruch, Ivonne M. C. M. Rietjens
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/14/7/1364