Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury

Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury

Traumatic spinal cord injury (SCI) is characterized by severe neuroinflammation and hampered neuroregeneration, which often leads to permanent neurological deficits. Current therapies include decompression surgery, rehabilitation, and in some instances, the use of corticosteroids. However, the golde...

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Bibliographic Details
Main Authors: Femke Mussen, Jana Van Broeckhoven, Niels Hellings, Melissa Schepers, Tim Vanmierlo
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
traumatic spinal cord injury
cAMP
phosphodiesterases
neuroinflammation
regeneration
Online Access:https://www.mdpi.com/1422-0067/24/9/8135

Internet

https://www.mdpi.com/1422-0067/24/9/8135

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