Mechanical Loading Promotes Calcification of Tissue-Engineered Bone In Vitro

Cyclic mechanical loading can stimulate bone cells in vivo, resulting in the mechano-adaptive osteogenic response of bone. The objective of this study was to investigate the capability of mechanical loading to promote three-dimensional osteoblastic calcification in vitro. A bone-like construct was m...

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Bibliographic Details
Main Author: Shigeo M. TANAKA
Format: Article
Language:English
Published: The Japan Society of Mechanical Engineers 2010-12-01
Series:Journal of Biomechanical Science and Engineering
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jbse/5/5/5_5_635/_pdf/-char/en