TGF-β1–induced endothelial-mesenchymal transition: a potential contributor to fibrotic remodeling in atrial fibrillation?
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide, with an unmet therapeutic need. Fibrotic remodeling, in which collagen-producing atrial fibroblasts play a crucial role, substantially contributes to arrhythmia promotion and progression. In this issue of the JCI, Lai, Tsai, a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-07-01
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Series: | The Journal of Clinical Investigation |
Online Access: | https://doi.org/10.1172/JCI161070 |