Nanoparticle-Mediated Interleukin-12 Cancer Gene Therapy

Interleukin-12 (Il-12) is a heterodimeric cytokine which has been proved to possess antitumor effects in various animal models via stimulating the immune system. The main problem associated with Il-12 protein delivery is its instability as well as cytotoxicity subsequent to systemic administration i...

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Bibliographic Details
Main Authors: Crispin Dass, Somayeh Hallaj-Nezhadi, Farzaneh Lotfipour
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-11-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/8532