Oxygen-Dependent Accumulation of Purine DNA Lesions in Cockayne Syndrome Cells

Oxygen-Dependent Accumulation of Purine DNA Lesions in Cockayne Syndrome Cells

Cockayne Syndrome (CS) is an autosomal recessive neurodegenerative premature aging disorder associated with defects in nucleotide excision repair (NER). Cells from CS patients, with mutations in <i>CSA</i> or <i>CSB</i> genes, present elevated levels of reactive oxygen specie...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Marios G. Krokidis, Mariarosaria D’Errico, Barbara Pascucci, Eleonora Parlanti, Annalisa Masi, Carla Ferreri, Chryssostomos Chatgilialoglu
التنسيق: مقال
اللغة:English
منشور في: MDPI AG 2020-07-01
سلاسل:Cells
الموضوعات:
CSA
CSB
oxygen concentration
free radicals
oxidatively generated DNA damage
isotope dilution LC-MS/MS
الوصول للمادة أونلاين:https://www.mdpi.com/2073-4409/9/7/1671

الانترنت

https://www.mdpi.com/2073-4409/9/7/1671

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