Activity-based protein profiling identifies alternating activation of enzymes involved in the bifidobacterium shunt pathway or mucin degradation in the gut microbiome response to soluble dietary fiber

Abstract While deprivation of dietary fiber has been associated with adverse health outcomes, investigations concerning the effect of dietary fiber on the gut microbiome have been largely limited to compositional sequence-based analyses or utilize a defined microbiota not native to the host. To exte...

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Bibliographic Details
Main Authors: Bryan J. Killinger, Christopher Whidbey, Natalie C. Sadler, Adrian J. DeLeon, Nathalie Munoz, Young-Mo Kim, Aaron T. Wright
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-022-00313-z