Effect of Chronic Intermittent Hypoxia on Angiotensin II Receptors in the Central Nervous System

Effect of Chronic Intermittent Hypoxia on Angiotensin II Receptors in the Central Nervous System

Chronic intermittent hypoxia (CIH) increases basal sympathetic nervous system activity, augments chemoreflex-induced sympathoexcitation, and raises blood pressure. All effects are attenuated by systemic or intracerebroventricular administration of angiotensin II type 1 receptor (AT1R) antagonists. T...

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Bibliographic Details
Main Authors: Barbara J. Morgan, Nicole Schrimpf, Morgan Rothman, Ann Mitzey, Mark S. Brownfield, Robert C. Speth, John M. Dopp
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:Clinical and Experimental Hypertension
Subjects:
immunohistochemistry
rostroventrolateral medulla
paraventricular nucleus of the hypothalamus
chemoreflex
sympathetic nervous system
blood pressure
rats
Online Access:http://dx.doi.org/10.1080/10641963.2018.1451536

Internet

http://dx.doi.org/10.1080/10641963.2018.1451536

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