Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques.

Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques.

HIV-infected infants are at an increased risk of progressing rapidly to AIDS in the first weeks of life. Here, we evaluated immunological and virological parameters in 25 SIV-infected infant rhesus macaques to understand the factors influencing a rapid disease outcome. Infant macaques were infected...

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Bibliographic Details
Main Authors: Matthew P Wood, Chloe I Jones, Adriana Lippy, Brian G Oliver, Brynn Walund, Katherine A Fancher, Bridget S Fisher, Piper J Wright, James T Fuller, Patience Murapa, Jakob Habib, Maud Mavigner, Ann Chahroudi, D Noah Sather, Deborah H Fuller, Donald L Sodora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009575

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https://doi.org/10.1371/journal.ppat.1009575

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