Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis.
Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated compared to other receptor tyrosine kinases. Here, we studied the effect of FGFR si...
Główni autorzy: | Frédéric Larrieu-Lahargue, Alana L Welm, Marion Bouchecareilh, Kari Alitalo, Dean Y Li, Andreas Bikfalvi, Patrick Auguste |
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Format: | Artykuł |
Język: | English |
Wydane: |
Public Library of Science (PLoS)
2012-01-01
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Seria: | PLoS ONE |
Dostęp online: | http://europepmc.org/articles/PMC3382584?pdf=render |
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