Differential methylation of microRNA encoding genes may contribute to high myopia

Differential methylation of microRNA encoding genes may contribute to high myopia

Introduction: High myopia (HM), an eye disorder with a refractive error ≤−6.0 diopters, has multifactorial etiology with environmental and genetic factors involved. Recent studies confirm the impact of alterations in DNA methylation and microRNAs (miRNAs) on myopia. Here, we studied the combined asp...

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Bibliographic Details
Main Authors: Joanna Swierkowska, Sangeetha Vishweswaraiah, Malgorzata Mrugacz, Uppala Radhakrishna, Marzena Gajecka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
DNA methylation
epigenetic changes
childhood myopia
early-onset high myopia
microRNA target genes
miRNA encoding genes
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1089784/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.1089784/full

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