Phosphorus metabolism in the brain of cognitively normal midlife individuals at risk for Alzheimer's disease

Phosphorus metabolism in the brain of cognitively normal midlife individuals at risk for Alzheimer's disease

Background: Neurometabolic abnormalities and amyloid-beta plaque deposition are important early pathophysiologic changes in Alzheimer's disease (AD). This study investigated the relationship between high-energy phosphorus-containing metabolites, glucose uptake, and amyloid plaque using phosphor...

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Bibliographic Details
Main Authors: Prodromos Parasoglou, Ricardo S. Osorio, Oleksandr Khegai, Zanetta Kovbasyuk, Margo Miller, Amanda Ho, Seena Dehkharghani, Thomas Wisniewski, Antonio Convit, Lisa Mosconi, Ryan Brown
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Neuroimage: Reports
Subjects:
Phosphorus magnetic resonance spectroscopy
Brain energy metabolism
Positron emission tomography
Online Access:http://www.sciencedirect.com/science/article/pii/S2666956022000459

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http://www.sciencedirect.com/science/article/pii/S2666956022000459

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