Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA

Background Combined treatment with all-trans-retinoic acid and chemotherapy is extremely efficient in patients with acute promyelocytic leukemia with t(15;17)/PML-RARA, but up to 15% of patients relapse.Design and Methods To further clarify the prognostic impact of parameters such as FLT3 mutations,...

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Bibliographic Details
Main Authors: Susanne Schnittger, Ulrike Bacher, Claudia Haferlach, Wolfgang Kern, Tamara Alpermann, Torsten Haferlach
Format: Article
Language:English
Published: Ferrata Storti Foundation 2011-12-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6152