Msx1+ stem cells recruited by bioactive tissue engineering graft for bone regeneration

Msx1+ stem cells recruited by bioactive tissue engineering graft for bone regeneration

Critical-sized bone defects still present clinical challenges. Here the authors show that transplantation of neurotrophic supplement-incorporated hydrogel grafts promote full-thickness regeneration of the calvarium and perform scRNA-seq to reveal contributing stem/progenitor cells, notably a residen...

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Bibliographic Details
Main Authors: Xianzhu Zhang, Wei Jiang, Chang Xie, Xinyu Wu, Qian Ren, Fei Wang, Xilin Shen, Yi Hong, Hongwei Wu, Youguo Liao, Yi Zhang, Renjie Liang, Wei Sun, Yuqing Gu, Tao Zhang, Yishan Chen, Wei Wei, Shufang Zhang, Weiguo Zou, Hongwei Ouyang
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32868-y

Internet

https://doi.org/10.1038/s41467-022-32868-y

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