Mechanisms of Metal-Induced Mitochondrial Dysfunction in Neurological Disorders
Metals are actively involved in multiple catalytic physiological activities. However, metal overload may result in neurotoxicity as it increases formation of reactive oxygen species (ROS) and elevates oxidative stress in the nervous system. Mitochondria are a key target of metal-induced toxicity, gi...
Main Authors: | Hong Cheng, Bobo Yang, Tao Ke, Shaojun Li, Xiaobo Yang, Michael Aschner, Pan Chen |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Toxics |
Subjects: | |
Online Access: | https://www.mdpi.com/2305-6304/9/6/142 |
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