A Comprehensive Study of De Novo Mutations on the Protein-Protein Interaction Interfaces Provides New Insights into Developmental Delay

A Comprehensive Study of De Novo Mutations on the Protein-Protein Interaction Interfaces Provides New Insights into Developmental Delay

Mutations, especially those at the protein-protein interaction (PPI) interface, have been associated with various diseases. Meanwhile, though de novo mutations (DNMs) have been proven important in neuropsychiatric disorders, such as developmental delay (DD), the relationship between PPI interface DN...

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Bibliographic Details
Main Authors: Dhruba Tara Maharjan, Weichen Song, Zhe Liu, Weidi Wang, Wenxiang Cai, Jue Chen, Fei Xu, Weihai Ying, Guan Ning Lin
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
developmental delay
de novo mutation
protein-protein interaction
PPI interface
protein interactome
PsymuKB
Online Access:https://www.mdpi.com/2218-273X/12/11/1643

Internet

https://www.mdpi.com/2218-273X/12/11/1643

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