Toward Pathogenic Biofilm Suppressors: Synthesis of Amino Derivatives of Pillar[5]arene and Supramolecular Assembly with DNA

Toward Pathogenic Biofilm Suppressors: Synthesis of Amino Derivatives of Pillar[5]arene and Supramolecular Assembly with DNA

New amino derivatives of pillar[5]arene were obtained in three stages with good yields. It was shown that pillar[5]arene containing thiaether and tertiary amino groups formed supramolecular complexes with low molecular weight model DNA. Pillar[5]arene formed complexes with a DNA nucleotide pair at a...

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Bibliographic Details
Main Authors: Yulia I. Aleksandrova, Dmitriy N. Shurpik, Viktoriya A. Nazmutdinova, Olga A. Mostovaya, Evgenia V. Subakaeva, Evgenia A. Sokolova, Pavel V. Zelenikhin, Ivan I. Stoikov
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
water-soluble pillar[5]arene
salmon sperm DNA
DNA compactification
gene transfection vector
antibacterial systems
biofilms
Online Access:https://www.mdpi.com/1999-4923/15/2/476

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https://www.mdpi.com/1999-4923/15/2/476

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