Investigating the alterations of endocannabinoidome signaling in the human small intestine in the context of obesity and type 2 diabetes

Investigating the alterations of endocannabinoidome signaling in the human small intestine in the context of obesity and type 2 diabetes

Background: Human studies have linked obesity-related diseases, such as type-2 diabetes (T2D), to the modulation of endocannabinoid signaling. Cannabinoid CB1 and CB2 receptor activation by the endocannabinoids (eCBs) 2-arachidonoylglycerol (2-AG) and N-arachidonoylethanolamine (AEA), both derived f...

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Bibliographic Details
Main Authors: Volatiana Rakotoarivelo, Bénédicte Allam-Ndoul, Cyril Martin, Laurent Biertho, Vincenzo Di Marzo, Nicolas Flamand, Alain Veilleux
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Obesity
Insulin resistance
Diabetes
Endocannabinoids
Monoacylglycerols (MAGs)
N-Acyl-ethanolamines (NAEs)
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024029992

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http://www.sciencedirect.com/science/article/pii/S2405844024029992

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