Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide.

<h4>Background</h4>N-butylidenephthalide (BP) exhibits antitumor effect in a variety of cancer cell lines. The objective of this study was to obtain additional insights into the mechanisms involved in BP induced cell death in human prostate cancer cells.<h4>Methods/principal findin...

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Bibliographic Details
Main Authors: Sheng-Chun Chiu, Shee-Ping Chen, Sung-Ying Huang, Mei-Jen Wang, Shinn-Zong Lin, Horng-Jyh Harn, Cheng-Yoong Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22470469/pdf/?tool=EBI