Dasatinib attenuates airway inflammation of asthma exacerbation in mice induced by house dust mites and dsRNA

Dasatinib attenuates airway inflammation of asthma exacerbation in mice induced by house dust mites and dsRNA

Asthma exacerbation is a significant clinical problem that causes resistance to corticosteroid therapy and elevated hospitalization risk. Src family kinases (SFKs) contribute to various steps of the immune response, such as airway inflammation in viral or bacterial infections and allergic asthma. Th...

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Bibliographic Details
Main Authors: Yuki Nishimoto, Daiki Ando, Kosuke Irie, Ikumi Kainuma, Yuki Katayama, Shiori Sato, Tomohiro Suzuki, Mai Harada, Tsubasa Yoshida, Kazuhiro Ito, Yasuo Kizawa
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Src family kinase
Corticosteroid resistance
Asthma
Exacerbation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822002023

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http://www.sciencedirect.com/science/article/pii/S2405580822002023

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