Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo

Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo

Background/Aims: Acute myeloid leukemia (AML) remains a hematologic malignancy with poor survival and a high risk of relapse, which is mainly caused by the emergence of multidrug resistance (MDR). The identification of novel agents to improve therapeutic strategies becomes important priority for AML...

詳細記述

書誌詳細
主要な著者: Yingyu Chen, Donghui Gan, Qinghua Huang, Xiaofeng Luo, Donghong Lin, Jianda Hu
フォーマット: 論文
言語:English
出版事項: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
シリーズ:Cellular Physiology and Biochemistry
主題:
Emodin
Cytarabine
Acute myeloid leukemia
Apoptosis
Multidrug resistance
Akt/ mTOR
ERK
Xenograft model
オンライン･アクセス:https://www.karger.com/Article/FullText/492544

インターネット

https://www.karger.com/Article/FullText/492544

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