Rational Design of a Protein Kinase A Nuclear-cytosol Translocation Reporter
Abstract Protein Kinase A (PKA) exists as a tetrameric holoenzyme which activates with increase of cAMP and plays an important role in many physiological processes including cardiac physiology, neuronal development, and adipocyte function. Although this kinase has been the subject of numerous biosen...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-020-66349-3 |